Sulfuryl chloride → 2-[(4-Methylphenoxy)methyl]thiophene-3-sulfonyl chloride

HRID 234477Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 234477
[CH3:1][C:2]1[CH:22]=[CH:21][C:5]([O:6][CH2:7][C:8]2[S:9][CH:10]=[CH:11][C:12]=2[S:13](C2NC=CC=2)(=[O:15])=[O:14])=[CH:4][CH:3]=1.[OH-].[Na+].CCO.S(Cl)([Cl:31])(=O)=O>>[CH3:1][C:2]1[CH:22]=[CH:21][C:5]([O:6][CH2:7][C:8]2[S:9][CH:10]=[CH:11][C:12]=2[S:13]([Cl:31])(=[O:15])=[O:14])=[CH:4][CH:3]=1

Komponenten

4

Edukt 3

HCID 24648Sulfuryl chlorideHCID 23692425Sodium hydroxide ethanolHCID 865839612-[(4-Methylphenoxymethyl]thiophene-3-sulfonyl}pyrrole

Produkt 1

HCID 234452572-[(4-Methylphenoxy)methyl]thiophene-3-sulfonyl chloride

Versuchsvorschrift

2-[(4-methylphenoxy)methyl]thiophene-3-sulfonyl chloride was prepared, as described in Example 64E, using N-{2-[(4-methylphenoxymethyl]thiophene-3-sulfonyl}pyrrole by basic hydrolysis (NaOH/EtOH) followed by conversion to the corresponding sulfonyl chloride, in yield.

Aufarbeitung

  1. customin yield

Quellen und Nachweise

ORD-Eintrag
ord-9f5b939a1dc144308375610f33650166
Quelldatensatz
uspto-grants-1997_01
Patentnummer
US05594021

Notizen zur Reaktion

Wird geladen…