[Cl:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[C:4](=[O:21])[N:5]([CH3:20])[C:6]1[N:7]2[CH:12]=[N:13][C:14]=1[C:15]([O:17]CC)=[O:16].O.[OH-].[Na+].Cl>C(O)C>[Cl:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[C:4](=[O:21])[N:5]([CH3:20])[C:6]1[N:7]2[CH:12]=[N:13][C:14]=1[C:15]([OH:17])=[O:16]Ethyl 6-chloro-4,5-dihydro-4-methyl-5-oxo-imidazo(1,5-a)quinazoline-3-carboxylate (2.27g,7.4mmol) in a mixture of 50ml of ethanol, 25ml of water and 4.6ml of 4M aquous sodium hydroxide was refluxed for 1h. Then the mixture was cooled to 0° C. and neutralized by addition of 4.6ml of 4M hydrochloric acid. The precipitate was filtered off, rinsed with water and dried to give 2.lg (100%) of 6-chloro-4,5-dihydro-4-methyl-5-oxo-imidazo(1.5-a)quinazoline- 3-carboxylic acid.
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