4-Chloro-alpha,alpha,alpha-trifluoro-3-nitrotoluene → 2-Nitro-1-phenoxy-4-(trifluoromethyl)benzene

HRID 235988

Reaktionsgleichung

Reaktionsgleichung von HRID 235988
C(=O)([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)OC.Cl[C:13]1[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=1[N+:23]([O-:25])=[O:24].CC1C(CN2CCC(N3CCC(N4C(=O)NC5C4=CC=CC=5)CC3)CC2)=CC=CC=1.C(=O)([O-])[O-]>>[C:5]1([O:4][C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[N+:23]([O-:25])=[O:24])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Komponenten

5

Edukt 4

HCID 84624-Chloro-alpha,alpha,alpha-trifluoro-3-nitrotolueneHCID 19660Carbonate IonHCID 139482Carbonic acid, methyl phenyl esterHCID 10092649Tbpb

Produkt 1

HCID 2459422-Nitro-1-phenoxy-4-(trifluoromethyl)benzeneAusbeute 99 %

Reaktionsbedingungen

Temperatur
150 °C

Versuchsvorschrift

A mixture of 3.8 g of methyl phenyl carbonate, 5.64 g of 4-chloro-3-nitrobenzotrifluoride, and 0.17 g of TBPB was heated at 150° C. for 1 hour. All of the carbonate was converted with a 99 percent yield of 2-nitro-4-trifluoromethylphenyl phenyl ether. Distillation of the product yielded 6.65 g (94 percent) of the ether, b.p. 148°-9° C./2 mm.

Quellen und Nachweise

ORD-Eintrag
ord-98fb5941a208442cbdd380a63fbbe737
Quelldatensatz
uspto-grants-1987_02
Patentnummer
US04642349

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