4-(2-(4-Methyl-3-nitrophenoxy)ethyl)morpholine → 2-Methyl-5-[2-(morpholin-4-yl)ethoxy]aniline

HRID 2360276Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2360276
[CH3:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)=[CH:4][C:3]=1[N+:17]([O-])=O>CO.[Pd]>[CH3:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)=[CH:4][C:3]=1[NH2:17]

Komponenten

4

Edukt 1

HCID 589298674-(2-(4-Methyl-3-nitrophenoxy)ethyl)morpholine

Produkt 1

HCID 393350392-Methyl-5-[2-(morpholin-4-yl)ethoxy]aniline

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

To the mixture of 4-(2-(4-methyl-3-nitrophenoxy)ethyl)morpholine (532 mg, 2 mmol) in MeOH (50 mL) was added 10% Pd/C (250 mg). The mixture was stirred under an atmosphere of H2 (balloon) overnight. The contents of the reaction mixture were then filtered and concentrated in vacuo to give the title product, which was used without further purification.

Aufarbeitung

  1. filtrationThe contents of the reaction mixture were then filtered
  2. concentrationconcentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-385118c164254ec5886257b7e6f813e1
Quelldatensatz
uspto-grants-2014_04
Patentnummer
US08686011B2

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