6-Amino-1-cyclopropyl-5-nitroso-2,4(1H,3H)-pyrimidinedione → 1-cyclopropyl-5,6-diamino-2,4-(1H,3H)-pyrimidinedione
Reaktionsgleichung
[NH2:1][C:2]1[N:7]([CH:8]2[CH2:10][CH2:9]2)[C:6](=[O:11])[NH:5][C:4](=[O:12])[C:3]=1[N:13]=O>CN(C=O)C.O=[Pt]=O>[CH:8]1([N:7]2[C:2]([NH2:1])=[C:3]([NH2:13])[C:4](=[O:12])[NH:5][C:6]2=[O:11])[CH2:10][CH2:9]1Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
15.9 g of 6-amino-1-cyclopropyl-5-nitroso-2,4-(1H,3H)-pyrimidinedione (III) was catalytically hydrogenated in 1 liter of DMF and in the presence of 0.1 g PtO2 for 4 hours and at room temperature and at a pressure of 200 kPa. The catalyst and the crystals were filtered off and washed with ethanol. Yield 12.9 g (87%) (IV).
Aufarbeitung
- filtrationThe catalyst and the crystals were filtered off
- washwashed with ethanol
Quellen und Nachweise
- ORD-Eintrag
- ord-81ce205520624aa6af6afae8157a87c8
- Quelldatensatz
- uspto-grants-1987_02
- Patentnummer
- US04644001
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