Hydrochloric Acid → Diisopropylamino-acetic acid hydrochloride

HRID 2364929Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2364929
C([O:5][C:6](=[O:15])[CH2:7][N:8]([CH:12]([CH3:14])[CH3:13])[CH:9]([CH3:11])[CH3:10])(C)(C)C.[ClH:16]>O>[ClH:16].[CH:9]([N:8]([CH2:7][C:6]([OH:15])=[O:5])[CH:12]([CH3:13])[CH3:14])([CH3:10])[CH3:11]

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 11333389HCID 11333389, Verbindung

Produkt 1

HCID 46735981Diisopropylamino-acetic acid hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

5.4 g (25 mMol) diisopropylamino-acetic acid tert-butylester 2 was stirred with 6.25 ml (75 mMol) 12 M HCl in 25 ml water for 2.5 h at 60° C. After distillation in vacuo of water and excess of HCl, the residue was dried with toluene azeotropically.

Aufarbeitung

  1. distillationAfter distillation in vacuo of water
  2. dry with materialexcess of HCl, the residue was dried with toluene azeotropically

Quellen und Nachweise

ORD-Eintrag
ord-ebb2f625df644252aacb55878745cfe1
Quelldatensatz
uspto-grants-2014_04
Patentnummer
US08697604B2

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