HCID 57517484, Verbindung → 1344684-60-1

HRID 2368081Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2368081
[N:1]([CH:4]([CH3:20])[CH2:5][CH2:6][CH:7]1[CH2:12][CH2:11][N:10]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:9][CH2:8]1)=[N+]=[N-]>CO.[Pd]>[NH2:1][CH:4]([CH3:20])[CH2:5][CH2:6][CH:7]1[CH2:12][CH2:11][N:10]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:9][CH2:8]1

Komponenten

4

Edukt 1

HCID 57517484HCID 57517484, Verbindung

Produkt 1

HCID 575174851344684-60-1Ausbeute 103,8 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

A suspension of tert-butyl 4-(3-azidobutyl)piperidine-1-carboxylate (3.81 g) and 5% palladium/carbon (containing water (50%), 800 mg) in methanol (100 mL) was stirred at room temperature for 15 hr under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound (3.59 g).

Aufarbeitung

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-a789f81dd182482882a7121e7fcd1e46
Quelldatensatz
uspto-grants-2014_04
Patentnummer
US08703758B2

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