(3-Aminopropyl)triethoxysilane → alpha-D-Mannopyranose

HRID 2369766

Reaktionsgleichung

Reaktionsgleichung von HRID 2369766
C1(NC2C(=O)C(=O)C=2)C=CC=CC=1.[OH:14][C@H:15]1[O:23][C@H:22]([CH2:24][OH:25])[C@@H:20]([OH:21])[C@H:18]([OH:19])[C@@H:16]1[OH:17].NCCC[Si](OCC)(OCC)OCC>C(O)C.O.C(N(CC)CC)C.CCO>[OH:14][C@H:15]1[O:23][C@H:22]([CH2:24][OH:25])[C@@H:20]([OH:21])[C@H:18]([OH:19])[C@@H:16]1[OH:17]

Komponenten

6

Edukt 2

HCID 13521(3-Aminopropyl)triethoxysilaneHCID 86678081alpha-Mannose phenylaminocyclobutenedione2×

Produkt 1

HCID 185698alpha-D-Mannopyranose

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 702EthanolLösungsmittelHCID 8471TriethylamineLösungsmittelHCID 19096565Water ethanolLösungsmittel

Versuchsvorschrift

α-mannose phenylaminocyclobutenedione (250 mg; 0.37 mmol) was dissolved in a mixture of Ethanol/H2O (3/2) (10 mL) and triethyamine (400 μL) was added dropwise to the solution of APTS (Aminopropyltriethoxysilane) grafted nanoparticles DB060 (250 mg in 10 ml of EtOH). The mixture was stirred during 16 h. The nanoparticles were then centrifugated and washed with water and ethanol and dried under vacuum to afford 232 mg of grafted nanoparticles. The concentration of α-mannose phenylaminocyclobutenedione grafted on the surface of the DB103 nanoaprticle is 0.089 mmol/g.

Aufarbeitung

  1. washwashed with water and ethanol
  2. customdried under vacuum
  3. customto afford 232 mg of grafted nanoparticles

Quellen und Nachweise

ORD-Eintrag
ord-b8eeaa78aaa64ca1b8ddeca525e5f66a
Quelldatensatz
uspto-grants-2014_04
Patentnummer
US08709747B2

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