HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Potassium Carbonate → 2-(2-Fluoroethyl)-4,4-dimethyl-1,2,3,4-tetrahydroisoquinolin-7-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 2-Fluoroethyl bromide | HCID 12982 | — |
| Edukt | 1,1-Difluoro-2-iodoethane | HCID 3833565 | — |
| Edukt | 4,4-Dimethyl-1,2,3,4-tetrahydroisoquinolin-7-amine | HCID 59021533 | — |
| Produkt | 2-(2-Fluoroethyl)-4,4-dimethyl-1,2,3,4-tetrahydroisoquinolin-7-amine | HCID 86670028 | — |
Reaktionsschritte
The title compound was prepared as described in Example 224B, substituting Example 224A and 1,1-difluoro-2-iodoethane with 4,4-dimethyl-1,2,3,4-tetrahydroisoquinolin-7-amine and 1-bromo-2-fluoroethane, respectively, and using 2.5 equivalent of K2CO3.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08710065B2 |
| Quelldatensatz | uspto-grants-2014_04 |
| ORD ID | ord-3739f900508f44468c459c910bdbdc5d |
| Quellennotiz | uspto-grants-2014_04 |