Dimethylamine → HCID 57271419, Verbindung

HRID 2372382Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2372382
[CH:1]([O:4][C:5]([C:7]1[CH:8]([CH3:28])[CH2:9][N:10]2[C:14](=[CH:15][C:16]([O:18]C3C=CC([N+]([O-])=O)=CC=3)=O)[CH2:13][S:12][C:11]=12)=[O:6])([CH3:3])[CH3:2].[CH3:29][NH:30][CH3:31]>O>[CH3:29][N:30]([CH3:31])[C:16](=[O:18])[CH:15]=[C:14]1[CH2:13][S:12][C:11]2=[C:7]([C:5]([O:4][CH:1]([CH3:2])[CH3:3])=[O:6])[CH:8]([CH3:28])[CH2:9][N:10]12

Komponenten

4

Edukt 2

HCID 674DimethylamineHCID 867455674-Nitrophenyl (7-Isopropoxycarbonyl-6-methyl-2,3,5,6-tetrahydropyrrolo[2,1-b]thiazol-3-ylidene)acetate

Produkt 1

HCID 57271419HCID 57271419, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

To 1.50 g of 4-nitrophenyl (7-isopropoxycarbonyl-6-methyl-2,3,5,6-tetrahydropyrrolo[2,1-b]thiazol-3-ylidene)acetate, was added 40 ml of a 25% aqueous solution of dimethylamine and the mixture was stirred at room temperature for 3 days. 40 ml of water was added thereto and the precipitate thus formed was collected by filtration, washed with water and dissolved in chloroform. After drying and distilling off the solvent, the crude crystals thus obtained were recrystallized from a solvent mixture of ether and n-hexane. Thus 0.6 g of the title compound was obtained.

Aufarbeitung

  1. customthe precipitate thus formed
  2. filtrationwas collected by filtration
  3. washwashed with water
  4. dissolutiondissolved in chloroform
  5. customAfter drying
  6. distillationdistilling off the solvent
  7. customthe crude crystals thus obtained
  8. customwere recrystallized from a solvent mixture of ether and n-hexane

Quellen und Nachweise

ORD-Eintrag
ord-62dd0dd976584d1f8d41b8de28be302a
Quelldatensatz
uspto-grants-1992_03
Patentnummer
US05098919

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