Gallium, chlorodimethyl- → o-Trifluoromethylbenzyldimethylgallium

HRID 2372542Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2372542
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH2:5]Br.C([Li])CCC.[Cl-].[CH3:19][Ga+:20][CH3:21]>CCOCC.CCCCCC.CCCCCC>[F:1][C:2]([F:12])([F:11])[C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH2:5][Ga:20]([CH3:21])[CH3:19]

Komponenten

6

Edukt 3

HCID 81329Gallium, chlorodimethyl-HCID 1230571-(Bromomethyl)-2-(trifluoromethyl)benzeneHCID 178418339Butyllithium

Produkt 1

HCID 14692906o-Trifluoromethylbenzyldimethylgallium

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 8058HexaneLösungsmittelHCID 21584099Diethylether hexaneLösungsmittel2×

Versuchsvorschrift

5.25 g (22 mmol) of o-trifluoromethylbenzyl bromide in 10 ml of ether/hexane are added at -50° to a mixture of 45 ml of ether/hexane (2:1) and 14.7 ml (1.5N =22 mmol) of n-butyllithium. After stirring for 15 minutes, 2.1 g (16 mmol) of dimethylgallium chloride in 20 ml of hexane are added. Then the reaction mixture is allowed to come to room temperature, it is stirred for 24 hours, and the LiCl is filtered off and the solvent removed. After sublimation in vacuo, o-trifluoromethylbenzyldimethylgallium is obtained with a Mp. 35°-38°.

Aufarbeitung

  1. customto come to room temperature
  2. stirringit is stirred for 24 hours
  3. filtrationthe LiCl is filtered off
  4. customthe solvent removed

Quellen und Nachweise

ORD-Eintrag
ord-7db2b241997c47a39394763b74c9d79f
Quelldatensatz
uspto-grants-1992_03
Patentnummer
US05099044

Notizen zur Reaktion

Wird geladen…