U 84935 → HCID 70059045, Verbindung

HRID 2372716Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2372716
[CH:1]1([C:4]2[O:8][N:7]=[C:6]([C:9]3[N:10]=[CH:11][N:12]4[C:21]5[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=5[C:15]5=[N:22][CH2:23][CH2:24][N:14]5[C:13]=34)[N:5]=2)[CH2:3][CH2:2]1.[C:25]([OH:34])(=[O:33])[C@@H:26]([C@H:28]([C:30]([OH:32])=[O:31])[OH:29])[OH:27]>ClCCl>[C:30]([C@@H:28]([C@H:26]([C:25]([OH:34])=[O:33])[OH:27])[OH:29])([OH:32])=[O:31].[CH:1]1([C:4]2[O:8][N:7]=[C:6]([C:9]3[N:10]=[CH:11][N:12]4[C:21]5[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=5[C:15]5=[N:22][CH2:23][CH2:24][N:14]5[C:13]=34)[N:5]=2)[CH2:3][CH2:2]1

Komponenten

4

Edukt 2

HCID 131796U 84935HCID 444305L-Tartaric acid

Produkt 1

HCID 70059045HCID 70059045, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

Equimolar amounts of 5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2,3-dihydrodiimidazo[1,5-a:1',2'-c]quinazoline (0.64 g) and L-tartaric acid (0.30 g) was stirred in dichloromethane (25 ml) until a clear solution was obtained. The solvent was removed by evaporation in vacuo and the residue was triturated with isopropyl alcohol. The crystalline precipitate was filtered off and recrystallized from ethanol yielding the title compound as pale crystals, m.p. 160°-163° C. (Compound 41).

Aufarbeitung

  1. customwas obtained
  2. customThe solvent was removed by evaporation in vacuo
  3. customthe residue was triturated with isopropyl alcohol
  4. filtrationThe crystalline precipitate was filtered off
  5. customrecrystallized from ethanol yielding the title compound as pale crystals, m.p. 160°-163° C. (Compound 41)

Quellen und Nachweise

ORD-Eintrag
ord-3ff57096c9694f3d9418f2558d2626f8
Quelldatensatz
uspto-grants-1992_03
Patentnummer
US05100895

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