3-Iodophthalic acid → 3-Iodophthalic anhydride

HRID 2377014

Reaktionsgleichung

Reaktionsgleichung von HRID 2377014
[I:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:4]([C:5]([OH:7])=O)[C:3]=1[C:11]([OH:13])=[O:12]>C(OC(=O)C)(=O)C>[I:1][C:2]1[C:3]2[C:11](=[O:12])[O:13][C:5](=[O:7])[C:4]=2[CH:8]=[CH:9][CH:10]=1

Komponenten

3

Edukt 1

HCID 2382313-Iodophthalic acid

Produkt 1

HCID 2820713-Iodophthalic anhydrideAusbeute 65,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7918Acetic AnhydrideLösungsmittel

Versuchsvorschrift

A solution of 3-iodophthalic acid (0.9 g, 3.08 mmol) in acetic anhydride (5 mL) was heated to reflux under nitrogen overnight. After cooling, the solvent was removed in vacuo and the residue purified by trituration with ethanol to give 4-iodo-2-benzofuran-1,3-dione (0.55 g, 65%).

Aufarbeitung

  1. temperatureto reflux under nitrogen overnight
  2. temperatureAfter cooling
  3. customthe solvent was removed in vacuo
  4. customthe residue purified by trituration with ethanol

Quellen und Nachweise

ORD-Eintrag
ord-06b41cd4add44d28838ce483980247c8
Quelldatensatz
uspto-grants-2008_12
Patentnummer
US07468393B2

Verknüpfte Notizen

Wird geladen…