Isopropylamine → Isopropylpent-4-enylamine

Reaktionsgleichung

Br[CH2:2][CH2:3][CH2:4][CH:5]=[CH2:6].[CH:7]([NH2:10])([CH3:9])[CH3:8]>>[CH:7]([NH:10][CH2:2][CH2:3][CH2:4][CH:5]=[CH2:6])([CH3:9])[CH3:8]

Komponenten

Edukt 2

HCID 6363Isopropylamine

HCID 707041-Pentene, 5-bromo-

Produkt 1

HCID 551578Isopropylpent-4-enylamineAusbeute 40 %

Reaktionsbedingungen

Temperatur: 60 °C

Versuchsvorschrift

5-Bromo-1-pentene (42.3 mmol) was added to isopropylamine (423 mmol), and the mixture was stirred at 60° C. for 48 h in the dark in a sealed tube. Then the volatiles were evaporated at reduced pressure and the crude residue was dissloved in 50 mL of diethyl ether and washed twice with water. The organic phase was dried over Na2SO4. Evaporation of the solvent gave N-isopropylpent-4-en-1-amine as brownish oil (40%) which was used without any further purification.

Aufarbeitung

customThen the volatiles were evaporated at reduced pressure
washwashed twice with water
dry with materialThe organic phase was dried over Na2SO4
customEvaporation of the solvent

Quellen und Nachweise

ORD-Eintrag: ord-a99b8692e57248e7be131da6ec9e231f
Quelldatensatz: uspto-grants-2008_12
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07470664B2

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