3,3-Diphenylacrylic acid → 3,3-Diphenylacryloyl chloride

HRID 2380693

Reaktionsgleichung

Reaktionsgleichung von HRID 2380693
P(Cl)(Cl)(Cl)(Cl)[Cl:2].[C:7]1([C:13]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:14][C:15](O)=[O:16])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>C(Cl)Cl>[C:7]1([C:13]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:14][C:15]([Cl:2])=[O:16])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Komponenten

4

Edukt 2

HCID 118263,3-Diphenylacrylic acidHCID 24819Phosphorus pentachloride

Produkt 1

HCID 112535443,3-Diphenylacryloyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

4.164 g of phosphorus pentachloride were added to 90 ml of a methylene chloride solution containing 4.485 g of 3,3-diphenylacrylic acid, which had previously been cooled at 0°-5° C. The reaction mixture was then stirred for one hour at room temperature, after which the solvent was distilled off under reduced pressure. The resulting residue was dissolved in 50 ml of toluene, and then the solvent was once again distilled off under reduced pressure. This procedure comprising dissolution and distillation was repeated once more. 3,3-Diphenylacryloyl chloride was obtained as a white solid. This crude product was immediately used in the next reaction.

Aufarbeitung

  1. temperaturehad previously been cooled at 0°-5° C
  2. distillationafter which the solvent was distilled off under reduced pressure
  3. dissolutionThe resulting residue was dissolved in 50 ml of toluene
  4. distillationthe solvent was once again distilled off under reduced pressure
  5. dissolutionThis procedure comprising dissolution and distillation

Quellen und Nachweise

ORD-Eintrag
ord-5a49bab8c4134c83bf270de8e97e78a4
Quelldatensatz
uspto-grants-1994_11
Patentnummer
US05369106

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