Diethanolamine → N,N-di-(2-hydroxyethyl) 3-(N-vinylformamido)propionamide

HRID 2383

Reaktionsgleichung

Reaktionsgleichung von HRID 2383
[CH:1]([N:3]([CH2:6][CH2:7][C:8]([O:10]C)=O)[CH:4]=[O:5])=[CH2:2].[NH:12]([CH2:16][CH2:17][OH:18])[CH2:13][CH2:14][OH:15].C[O-].[Na+]>CO>[OH:15][CH2:14][CH2:13][N:12]([CH2:16][CH2:17][OH:18])[C:8](=[O:10])[CH2:7][CH2:6][N:3]([CH:1]=[CH2:2])[CH:4]=[O:5]

Komponenten

5

Edukt 3

HCID 8113DiethanolamineHCID 10942334Sodium MethoxideHCID 10964771methyl 3-(N-vinylformamido)propionate

Produkt 1

HCID 53864890N,N-di-(2-hydroxyethyl) 3-(N-vinylformamido)propionamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Reaktionsbedingungen

Temperatur
90 °C

Versuchsvorschrift

A 50 mL single-neck round bottom flask equipped with a distillation head was charged with 15.1 grams (0.096 mole) of methyl 3-(N-vinylformamido)propionate, 9.95 grams (0.09 mole) of diethanolamine and 0.15 gram of 25% sodium methoxide in methanol solution. The mixture was stirred at 90° C. for 2 hours and the generated methanol was removed by distillation at reduced pressure. Both proton NMR and GC analyses indicated approximately a 90% conversion to the titled product.

Aufarbeitung

  1. customA 50 mL single-neck round bottom flask equipped with a distillation head
  2. customthe generated methanol was removed by distillation at reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-5d0de86ea40e4c07a7ac73d256823ecf
Quelldatensatz
uspto-grants-1998_03
Patentnummer
US05728878

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