Ethylamine → N-[4-(1-Aminoethyl)-2-fluorophenyl]methanesulfonamide
Reaktionsgleichung
[F:1][C:2]1[CH:3]=[C:4]([C:13](=[N:15]O)[CH3:14])[CH:5]=[CH:6][C:7]=1[NH:8][S:9]([CH3:12])(=[O:11])=[O:10].C(N)C>>[F:1][C:2]1[CH:3]=[C:4]([CH:13]([NH2:15])[CH3:14])[CH:5]=[CH:6][C:7]=1[NH:8][S:9]([CH3:12])(=[O:11])=[O:10]Komponenten
3
Versuchsvorschrift
Through similar procedure to that in Example 97-3 excepting using 3′-fluoro-4′-(methylsulfonylamino)acetophenone oxime (13-9) as a starting material, 3′-Fluoro-4-(methylsulfonylamino)phenyl]ethyl amine (13-12, MK-232) having following physicochemical properties was synthesized:
Aufarbeitung
- customwas synthesized
Quellen und Nachweise
- ORD-Eintrag
- ord-ddeb4398d3034bb3b7a15adfe9e04b77
- Quelldatensatz
- uspto-grants-2014_02
- Patentnummer
- US08642657B2
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