6-Nitro-2,3-dihydro-1H-inden-1-amine--hydrogen chloride (1/1) → HCID 23298452, Verbindung

HRID 2393551Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2393551
[ClH:1].[N+:2]([C:5]1[CH:13]=[C:12]2[C:8]([CH2:9][CH2:10][CH:11]2[NH2:14])=[CH:7][CH:6]=1)([O-])=O>CO.[Pd]>[ClH:1].[NH2:2][C:5]1[CH:13]=[C:12]2[C:8]([CH2:9][CH2:10][CH:11]2[NH2:14])=[CH:7][CH:6]=1

Komponenten

4

Edukt 1

HCID 232984006-Nitro-2,3-dihydro-1H-inden-1-amine--hydrogen chloride (1/1)

Produkt 1

HCID 23298452HCID 23298452, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

To a solution of 6-nitro-1-aminoindane hydrochloride (1.00 g, 4.66 mmol) in MeOH (100 ml) was added a catalytic amount of 10% Pd/C. The mixture was hydrogenated at 50 psi for 1 hr, filtered through celite, and concentrated to give 6-amino-1-aminoindane hydrochloride which was homogeneous by TLC and used immediately in the next step.

Aufarbeitung

  1. filtrationfiltered through celite
  2. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-6ffb8232c8d04f53b95350857f394d76
Quelldatensatz
uspto-grants-1998_09
Patentnummer
US05807886

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