4-(3,4-Dichlorophenyl)-3-buten-2-one → HCID 53715145, Verbindung

HRID 2395597Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2395597
[BH4-].[Na+].[Cl:3][C:4]1[CH:5]=[C:6]([CH:11]=[CH:12][C:13](=[O:15])[CH3:14])[CH:7]=[CH:8][C:9]=1[Cl:10]>C(O)C>[Cl:3][C:4]1[CH:5]=[C:6]([CH:11]=[CH:12][CH:13]([OH:15])[CH3:14])[CH:7]=[CH:8][C:9]=1[Cl:10]

Komponenten

4

Edukt 2

HCID 3265634-(3,4-Dichlorophenyl)-3-buten-2-oneHCID 4311764Sodium borohydride

Produkt 1

HCID 53715145HCID 53715145, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

2.25 g (0.0599 mol) of NaBH4 are added portionwise at room temperature to a suspension of 39.2 g (0.182 mol) of 4-(3,4-dichlorophenyl)-3-buten-2-one in 900 ml of ethanol and the mixture is stirred overnight at room temperature. The mixture is concentrated under vacuum, taken up in water, extracted with methylene chloride, washed with water, dried over sodium sulphate, filtered and evaporated under vacuum. The product obtained is used without subsequent purification in the following stage. Yd.: 35.2 g (89%)

Aufarbeitung

  1. concentrationThe mixture is concentrated under vacuum
  2. extractionextracted with methylene chloride
  3. washwashed with water
  4. dry with materialdried over sodium sulphate
  5. filtrationfiltered
  6. customevaporated under vacuum
  7. customThe product obtained
  8. customis used without subsequent purification in the following stage

Quellen und Nachweise

ORD-Eintrag
ord-cf60c2991c014088927f434838cef0e5
Quelldatensatz
uspto-grants-1996_02
Patentnummer
US05489592

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