Phosphorus pentachloride → HCID 178479351, Verbindung

HRID 2398626Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2398626
[ClH:1].[C:2]([NH:10][CH2:11][C:12]([OH:14])=O)(=[NH:9])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.P(Cl)(Cl)(Cl)(Cl)[Cl:16]>C(Cl)Cl>[ClH:16].[C:2]([NH:10][CH2:11][C:12]([Cl:1])=[O:14])(=[NH:9])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Komponenten

4

Edukt 2

HCID 24819Phosphorus pentachlorideHCID 178479352HCID 178479352, Verbindung

Produkt 1

HCID 178479351HCID 178479351, VerbindungAusbeute 99 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To benzimidoylaminoacetic acid hydrochloride (2.2 g., 10 mmoles) in 40 ml. of dry methylene chloride is added 2.5 g. (12 mmoles) of phosphorous pentachloride, and the reaction mixture allowed to stir overnight at room temperature. The product is filtered, washed successively with methylene chloride (50 ml. ), chloroform 2× 75 ml.) and hexane (50 ml.) and dried in vacuo, 2.5 g. (99% yield).

Aufarbeitung

  1. filtrationThe product is filtered
  2. washwashed successively with methylene chloride (50 ml. ), chloroform 2× 75 ml
  3. dry with material) and hexane (50 ml.) and dried in vacuo, 2.5 g

Quellen und Nachweise

ORD-Eintrag
ord-8472ed6ac61a4e67b131e5ed0c83f3cf
Quelldatensatz
uspto-grants-1977_05
Patentnummer
US04025506

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