Ammonium Hydroxide → 6-Aminopyridine-3-sulfonamide
Reaktionsgleichung
Cl[C:2]1[N:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[NH4+:12].[OH-]>[Cl-].[Na+].O>[NH2:12][C:2]1[N:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][CH:3]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 110 °C
Versuchsvorschrift
6-Chloropyridine-3-sulfonic acid amide (200 mg, 1 mmol) was placed in a sealed tube with 2 mL 28% aq. NH4OH and heated to 110° C. for 4 h. The mixture was diluted with brine and the title compound was collected as a solid (120 mg, 67%).
Aufarbeitung
- customthe title compound was collected as a solid (120 mg, 67%)
Quellen und Nachweise
- ORD-Eintrag
- ord-99ba472de0b444089f6d7083198c06b6
- Quelldatensatz
- uspto-grants-2014_08
- Patentnummer
- US08796313B2
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