HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-Cbz-d-alanine → Phenylmethyl{(1R)-1-[6-bromo-3-({[2-(trimethylsilyl)ethyl]oxy}methyl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}({[2-(trimethylsilyl)ethyl]oxy}methyl)carbamate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-Cbz-d-alanine | HCID 70832 | — |
| Edukt | 5-Bromopyridine-2,3-diamine | HCID 691156 | — |
| Edukt | 2-Chloromethyl 2-(trimethylsilyl)ethyl ether | HCID 2724271 | — |
| Produkt | Phenylmethyl{(1R)-1-[6-bromo-3-({[2-(trimethylsilyl)ethyl]oxy}methyl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}({[2-(trimethylsilyl)ethyl]oxy}methyl)carbamate | HCID 68773284 | — |
Reaktionsschritte
Synthesized according to the method of reagent preparation 19 by using 5-bromo-2,3-diaminopyridine and N-(benzyloxycarbonyl)-D-alanine in step 1 and 2-(trimethylsilyl)ethoxymethyl chloride in step 3. MS (EI) for C28H43BrN34O4Si2: 636 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08648066B2 |
| Quelldatensatz | uspto-grants-2014_02 |
| ORD ID | ord-051b6384e3ef49d690af3c5d455552cf |
| Quellennotiz | uspto-grants-2014_02 |