Phosphorus oxychloride → 7-[2-methoxyimino-2-{2-(2,2,2-trifluoroacetamido)thiazol-4-yl}acetamido]-3-[1-(2-carboxy-2-methoxyiminoethyl)-1H-tetrazol-5-yl]thiomethyl-3-cephem-4-carboxylic acid

Reaktionsgleichung

[CH3:1][O:2][N:3]=[C:4]([C:8]1[N:9]=[C:10]([NH:13][C:14](=[O:19])[C:15]([F:18])([F:17])[F:16])[S:11][CH:12]=1)[C:5]([OH:7])=O.C[N+](C)=CCl.[Cl-].P(Cl)(Cl)(Cl)=O.[NH2:31][CH:32]1[C:57](=[O:58])[N:34]2[C:35]([C:54]([OH:56])=[O:55])=[C:36]([CH2:39][S:40][C:41]3[N:45]([CH2:46][C:47]([C:51]([OH:53])=[O:52])=[N:48][O:49][CH3:50])[N:44]=[N:43][N:42]=3)[CH2:37][S:38][C@H:33]12.C(=O)(O)[O-].[Na+]>C(OCC)(=O)C.O1CCCC1.O.CC(C)=O.CN(C=O)C>[CH3:1][O:2][N:3]=[C:4]([C:8]1[N:9]=[C:10]([NH:13][C:14](=[O:19])[C:15]([F:18])([F:17])[F:16])[S:11][CH:12]=1)[C:5]([NH:31][CH:32]1[C:57](=[O:58])[N:34]2[C:35]([C:54]([OH:56])=[O:55])=[C:36]([CH2:39][S:40][C:41]3[N:45]([CH2:46][C:47]([C:51]([OH:53])=[O:52])=[N:48][O:49][CH3:50])[N:44]=[N:43][N:42]=3)[CH2:37][S:38][C@H:33]12)=[O:7]