Acetic Acid → HCID 53728512, Verbindung
Reaktionsgleichung
[CH3:1][N:2]([CH3:7])[C:3](=[S:6])[NH:4][NH2:5].[C:8]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([C:17](=O)[CH3:18])[N:12]=1)(=O)[CH3:9].C(O)(=O)C>CCO>[CH3:1][N:2]([CH3:7])[C:3](=[S:6])[NH:4][N:5]=[C:8]([C:11]1[N:12]=[C:13]([C:17](=[N:5][NH:4][C:3]([N:2]([CH3:7])[CH3:1])=[S:6])[CH3:18])[CH:14]=[CH:15][CH:16]=1)[CH3:9]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of 4,4-dimethylthiosemicarbazide (2.70 g, 0.022 mol) and 2,6-diacetylpyridine (1.63 g, 0.10 mol) in 95% EtOH (45 ml) containing glacial acetic acid (0.5 ml) was heated by a steam bath for 1 h and 10 min and allowed to cool to ambient temperature. The yellow precipitate was collected by filtration, washed with 95% EtOH, and subsequently recrystallized from toluene: yield 2.72 g (73%); mp 215° (dec).