Veratrole → N-[2-[bis(1-methylethyl)amino]ethyl]-3,4-dimethoxy-N-(1-methylethyl)-benzenesulfonamide

HRID 2413999Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2413999
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([S:11](Cl)(=[O:13])=[O:12])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].C1(OC)C(=CC=CC=1)OC.ClS(O)(=O)=O.[CH:30]([N:33]([CH:40]([CH3:42])[CH3:41])[CH2:34][CH2:35][NH:36][CH:37]([CH3:39])[CH3:38])([CH3:32])[CH3:31]>>[CH3:42][CH:40]([N:33]([CH:30]([CH3:32])[CH3:31])[CH2:34][CH2:35][N:36]([CH:37]([CH3:39])[CH3:38])[S:11]([C:5]1[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=1)(=[O:13])=[O:12])[CH3:41]

Komponenten

5

Edukt 4

HCID 7043VeratroleHCID 24638Chlorosulfonic acidHCID 66797N,N,N'-TriisopropylethylenediamineHCID 27341833,4-Dimethoxybenzenesulfonyl chloride

Produkt 1

HCID 14096741N-[2-[bis(1-methylethyl)amino]ethyl]-3,4-dimethoxy-N-(1-methylethyl)-benzenesulfonamide

Versuchsvorschrift

3,4-Dimethoxybenzene sulfonyl chloride, prepared from veratrole and chlorosulfonic acid was reacted with N,N,N'-triisopropyl ethylene diamine following the procedure of Example 1. The reaction was worked up and the crude product chromatographed on alumina with ethyl acetate. The pure product was obtained, m.r. 69°-71° C.

Aufarbeitung

  1. customthe crude product chromatographed on alumina with ethyl acetate
  2. customThe pure product was obtained
  3. custom69°-71° C.

Quellen und Nachweise

ORD-Eintrag
ord-4187c3dcec7a4b8b91d5168270a89606
Quelldatensatz
uspto-grants-1988_01
Patentnummer
US04720580

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