4-Bromo-2-ethenyl-1-fluorobenzene → 4-Bromo-2-ethyl-1-fluorobenzene

HRID 2415256Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2415256
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[C:4]([CH:9]=[CH2:10])[CH:3]=1>C(OCC)(=O)C.[Pd]>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[C:4]([CH2:9][CH3:10])[CH:3]=1

Komponenten

4

Edukt 1

HCID 219339834-Bromo-2-ethenyl-1-fluorobenzene

Produkt 1

HCID 226410254-Bromo-2-ethyl-1-fluorobenzene

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

The yellow oil from step A (2.8 g, 10 mmol) was dissolved in Ethyl acetate (200 mL). Palladium-on-carbon (10%, 250 mg) was added and the mixture was hydrogenated under 1 atmosphere until TLC showed complete reaction. The mixture was filtered and the filtrate was concentrated to give an oil. 2.4 g, 87%.

Aufarbeitung

  1. customreaction
  2. filtrationThe mixture was filtered
  3. concentrationthe filtrate was concentrated
  4. customto give an oil

Quellen und Nachweise

ORD-Eintrag
ord-5c9659d2b24b40b89f0b8d48f5bfa4d3
Quelldatensatz
uspto-grants-2004_11
Patentnummer
US06818663B2

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