1,3-Benzenediamine, N1,N1-dimethyl-, hydrochloride (1:2) → 4-chloro-N-(3-dimethylaminophenyl)-3-(4-propylbenzamido)benzamide

HRID 2415704

Reaktionsgleichung

Reaktionsgleichung von HRID 2415704
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[NH:11][C:12](=[O:22])[C:13]1[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][CH3:21])=[CH:15][CH:14]=1.Cl.Cl.[CH3:25][N:26]([CH3:34])[C:27]1[CH:28]=[C:29]([CH:31]=[CH:32][CH:33]=1)[NH2:30]>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:30][C:29]2[CH:31]=[CH:32][CH:33]=[C:27]([N:26]([CH3:34])[CH3:25])[CH:28]=2)=[O:7])=[CH:4][C:3]=1[NH:11][C:12](=[O:22])[C:13]1[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][CH3:21])=[CH:15][CH:14]=1

Komponenten

3

Edukt 2

HCID 771241,3-Benzenediamine, N1,N1-dimethyl-, hydrochloride (1:2)HCID 226361294-Chloro-3-(4-propylbenzamido)benzoyl chloride

Produkt 1

HCID 98892214-chloro-N-(3-dimethylaminophenyl)-3-(4-propylbenzamido)benzamide

Versuchsvorschrift

Using an analogous procedure to that described in Example 1, 4-chloro-3-(4-propylbenzamido)benzoyl chloride was reacted with 3-dimethylamino aniline dihydrochloride to give the title compound; NMR Spectrum: (DMSOd6) 0.9 (t, 3H), 1.18 (t, 2H), 1.69 (m, 2H), 2.99 (s, 6H), 7.0 (d, 1H), 7.2-7.5 (m, 4H) 7.64-7.8 (m, 3H), 7.84 (d, 1H), 8.0 (m, 2H), 8.19 (s, 1H); Mass Spectrum: M+H+ 436 and 438.

Quellen und Nachweise

ORD-Eintrag
ord-c3245b290fc54d88976e4a5631543b4a
Quelldatensatz
uspto-grants-2004_11
Patentnummer
US06821965B1

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