Ammonium Hydroxide → 4-(Aminomethyl)oxan-4-ol

HRID 241651

Reaktionsgleichung

Reaktionsgleichung von HRID 241651
[O:1]1[C:3]2([CH2:8][CH2:7][O:6][CH2:5][CH2:4]2)[CH2:2]1.[NH4+:9].[OH-]>CO>[NH2:9][CH2:2][C:3]1([OH:1])[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1

Komponenten

4

Edukt 2

HCID 14923Ammonium HydroxideHCID 1604391,6-Dioxaspiro[2.5]octane

Produkt 1

HCID 436087544-(Aminomethyl)oxan-4-ol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

The methanol solution of 1,6-dioxaspiro[2.5]octane (3.15 g, 27.6 mmol) was added to the 25% ammonia aqueous solution (50.0 mL, 27.6 mmol) at 0° C. The mixture was warmed to room temperature and stirred for 18 h. The reaction mixture was concentrated in vacuo. The crude product was used for next step reaction without purification.

Aufarbeitung

  1. concentrationThe reaction mixture was concentrated in vacuo
  2. customThe crude product was used for next step reaction without purification

Quellen und Nachweise

ORD-Eintrag
ord-fc00036b66ec41eeb5e44cf2df03e5b5
Quelldatensatz
uspto-grants-2014_02
Patentnummer
US08653063B2

Verknüpfte Notizen

Wird geladen…