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HRID 241733Erstellt: 25. Oktober 2026

Piperidine → 3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-5-(2-oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-one

https://huagongshe.com/reaction/241733

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPiperidineHCID 8082—
Edukt3,5-Dimethyl-1H-pyrrole-2-carbaldehydeHCID 270465—
Edukt5-(2-Oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-oneHCID 66636156—
LösungsmittelEthanolHCID 702—
Produkt3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-5-(2-oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-oneHCID 66636332—

Reaktionsschritte

A solution of 5-(2-oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-one (4.3 mmoles), 3,5-dimethyl-1H-pyrrole-2-carbaldehyde (5.17 mmoles) and piperidine (3 mmoles) in ethanol (30 ml) is heated at reflux for 24 hours. The solid formed is filtered off, washed with ethanol, with water and then with ethanol and dried in vacuo to yield the title product.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08653073B2
Quelldatensatzuspto-grants-2014_02
ORD IDord-aec92611ce764018841a7c927e0ad948
Quellennotizuspto-grants-2014_02