Acetic Anhydride → HCID 20269005, Verbindung

HRID 2417851Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2417851
[OH:1][CH:2]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[NH:7][C:6](=[O:14])[CH2:5][CH2:4][CH2:3]1.[C:15](OC(=O)C)(=[O:17])[CH3:16]>>[C:15]([O:1][CH:2]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[NH:7][C:6](=[O:14])[CH2:5][CH2:4][CH2:3]1)(=[O:17])[CH3:16]

Komponenten

3

Edukt 2

HCID 7918Acetic AnhydrideHCID 20269010HCID 20269010, Verbindung

Produkt 1

HCID 20269005HCID 20269005, Verbindung

Versuchsvorschrift

A solution of 6-hydroxy-3,4,5,6-tetrahydro-1-benzazocin-2-(1H)one (9.2 g) in acetic anhydride (200 ml) is maintained at 80° C. for 3 hours. The reaction mixture is cooled to room temperature and the solvents removed under reduced pressure. Ether (300 ml) is added, and their resulting solution washed with water (150 ml) and dried over magnesium sulfate. The solvent is removed under reduced pressure to give 6-acetoxy-3,4,5,6-tetrahydro-1-benzazocin-2(1H)-one.

Aufarbeitung

  1. customthe solvents removed under reduced pressure
  2. additionEther (300 ml) is added
  3. customtheir resulting solution
  4. washwashed with water (150 ml)
  5. dry with materialdried over magnesium sulfate
  6. customThe solvent is removed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-4d58a634ffca4eb583c91d2dbaa4c7f9
Quelldatensatz
uspto-grants-1984_09
Patentnummer
US04470988

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