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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2422594Erstellt: 26. Oktober 2026

Methylamine → 2-[4-(1-Cyclobutyl-4-piperidinyloxy)phenyl]-3-methylpyrido[2,3-d]-pyrimidin-4(3H)-one

https://huagongshe.com/reaction/2422594

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethylamineHCID 6329—
Edukt2-Aminonicotinic acidHCID 72930—
Edukt4-[(1-Cyclobutyl-4-piperidinyl)oxy]benzaldehydeHCID 86624461—
Produkt2-[4-(1-Cyclobutyl-4-piperidinyloxy)phenyl]-3-methylpyrido[2,3-d]-pyrimidin-4(3H)-oneHCID 11625293—

Reaktionsschritte

The entitled compound was obtained according to the method of Example 15 but starting from 2-aminonicotinic acid, methylamine and 4-[(1-cyclobutyl-4-piperidinyl)oxy]benzaldehyde. The obtained compound was recrystallized from diethyl ether to give a colorless solid (m.p. 146.0-150.0° C.).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07960394B2
Quelldatensatzuspto-grants-2011_06
ORD IDord-4b341d4ba8d44b6881488bd26f6acc32
Quellennotizuspto-grants-2011_06