Propionic anhydride → 6-(4-Methoxy-2-propylaminophenyl)-5,6,7,8-tetrahydronaphthalen-2-ol
Reaktionsgleichung
[NH2:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[CH:10]1[CH2:19][CH2:18][C:17]2[CH:16]=[C:15]([OH:20])[CH:14]=[CH:13][C:12]=2[CH2:11]1.[C:21](OC(=O)CC)(=O)[CH2:22][CH3:23]>>[CH3:9][O:8][C:6]1[CH:5]=[CH:4][C:3]([CH:10]2[CH2:19][CH2:18][C:17]3[CH:16]=[C:15]([OH:20])[CH:14]=[CH:13][C:12]=3[CH2:11]2)=[C:2]([NH:1][CH2:21][CH2:22][CH3:23])[CH:7]=1Komponenten
3
Versuchsvorschrift
Synthesized from 6-(2-amino-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol (500 mg) and propionic anhydride (1 ml) according to an analogous synthetic method to Example 36, the title compound (270 mg) was obtained.
Quellen und Nachweise
- ORD-Eintrag
- ord-02cc5077810b4972969ced7f0a087f4f
- Quelldatensatz
- uspto-grants-2011_06