4-Nitrobenzoic Acid → N-(2,4-dimethoxyphenyl)-4-nitrobenzamide

Reaktionsgleichung

[CH3:1][O:2][C:3]1[CH:9]=[C:8]([O:10][CH3:11])[CH:7]=[CH:6][C:4]=1[NH2:5].[N+:12]([C:15]1[CH:23]=[CH:22][C:18]([C:19](O)=[O:20])=[CH:17][CH:16]=1)([O-:14])=[O:13]>>[N+:12]([C:15]1[CH:16]=[CH:17][C:18]([C:19]([NH:5][C:4]2[CH:6]=[CH:7][C:8]([O:10][CH3:11])=[CH:9][C:3]=2[O:2][CH3:1])=[O:20])=[CH:22][CH:23]=1)([O-:14])=[O:13]

Komponenten

Edukt 2

HCID 61084-Nitrobenzoic Acid

HCID 176522,4-Dimethoxyaniline

Produkt 1

HCID 710798N-(2,4-dimethoxyphenyl)-4-nitrobenzamideAusbeute 91,3 %

Versuchsvorschrift

Using 2,4-dimethoxyaniline (2.53 g, 16.0 mmol) and 4-nitrobenzoic acid (2.50 g, 14.8 mmol), the procedure of Reference Example 16 was repeated to obtain 3.72 g (91.3%) of the title compound in the form of yellow needle crystals.

Quellen und Nachweise

ORD-Eintrag: ord-5c35a8197eab49d69e7416ffbe7e9d87
Quelldatensatz: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US05728835

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