Water → 4-(2-Hydroxyacetyl)benzonitrile

HRID 2427141Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2427141
Br[CH2:2][C:3]([C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][CH:6]=1)=[O:4].[OH2:13]>C(#N)C>[OH:13][CH2:2][C:3]([C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][CH:6]=1)=[O:4]

Komponenten

4

Edukt 2

HCID 962WaterHCID 986544-(Bromoacetyl)benzonitrile

Produkt 1

HCID 179928864-(2-Hydroxyacetyl)benzonitrile

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

A solution of 1 g of 4-(2-bromoacetyl)benzonitrile in acetonitrile (5 mL) and water (10 mL) is treated under microwave irradiation (125° C., 50 min) The same experiment is conducted five times. All the vials are collected, extracted with ethyl ether, dried over magnesium sulfate and concentrated under vacuum to give the desired compound.

Aufarbeitung

  1. customAll the vials are collected
  2. extractionextracted with ethyl ether
  3. dry with materialdried over magnesium sulfate
  4. concentrationconcentrated under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-fc19a66bb1db4d53855eabf0420fa6a8
Quelldatensatz
uspto-grants-2011_06
Patentnummer
US07968581B2

Notizen zur Reaktion

Wird geladen…