m-Chloroperbenzoic acid → Methyl thieno[3,4-b]thiophene-2-carboxylate

HRID 242764Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 242764
[CH3:1][O:2][C:3]([C:5]1[S:9][C:8]2[CH2:10][S:11][CH2:12][C:7]=2[CH:6]=1)=[O:4].C1C=C(Cl)C=C(C(OO)=O)C=1>C(OCC)(=O)C.C(=O)=O>[S:9]1[C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:6][C:7]2=[CH:12][S:11][CH:10]=[C:8]12

Komponenten

5

Edukt 2

HCID 70297m-Chloroperbenzoic acidHCID 3441857Methyl 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate

Produkt 1

HCID 19007653Methyl thieno[3,4-b]thiophene-2-carboxylate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 280Carbon DioxideLösungsmittelHCID 8857Ethyl AcetateLösungsmittel2×

Versuchsvorschrift

A solution of 2.0 g (10 mmol) (3) in 30 mL ethyl acetate was stirred and cooled down in dry ice bath. MCPBA (1.75 g, 10 mmol) in 30 mL ethyl acetate was added dropwise to the reaction solution. After the addition, the mixture was kept stirring for overnight. Then the solvent was removed by evaporation and the residue contained a crude product of (4) and 3-chlorobenzoic acid.

Aufarbeitung

  1. additionAfter the addition
  2. customThen the solvent was removed by evaporation

Quellen und Nachweise

ORD-Eintrag
ord-c57d31ad389d49c883de7ca97a887f21
Quelldatensatz
uspto-grants-2014_02
Patentnummer
US08653228B2

Notizen zur Reaktion

Wird geladen…