Benzoyl Peroxide → HCID 57949559, Verbindung

HRID 2427677Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2427677
[CH3:1][O:2][C:3](=[O:16])[C:4]1[C:9]([CH3:10])=[CH:8][C:7]([Cl:11])=[CH:6][C:5]=1[C:12]([F:15])([F:14])[F:13].[Br:17]NC(=O)CCC(N)=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[CH3:1][O:2][C:3](=[O:16])[C:4]1[C:5]([C:12]([F:14])([F:13])[F:15])=[CH:6][C:7]([Cl:11])=[CH:8][C:9]=1[CH2:10][Br:17]

Komponenten

5

Edukt 3

HCID 7187Benzoyl PeroxideHCID 9834204N-BromosuccinamideHCID 579494324-Chloro-2-trifluoromethyl-6-methyl-benzoic acid methyl ester

Produkt 1

HCID 57949559HCID 57949559, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 5943Carbon TetrachlorideLösungsmittel

Versuchsvorschrift

A mixture of 4-chloro-2-trifluoromethyl-6-methyl-benzoic acid methyl ester (1.6 g, 6.3 mmol), N-bromosuccinamide (1.23 g, 6.93 mmol), and benzoyl peroxide (0.050 g, 0.20 mmol) in carbon tetrachloride (50 mL) was heated at reflux until majority of ester was consumed (as analyzed by GC/MS). The resulting mixture was filtered and the filtrate concentrated to afforded 2-bromomethyl-4-chloro-6-trifluoromethyl-benzoic acid methyl ester. The material was used without further purification.

Aufarbeitung

  1. temperaturewas heated
  2. customwas consumed (as analyzed by GC/MS)
  3. filtrationThe resulting mixture was filtered
  4. concentrationthe filtrate concentrated

Quellen und Nachweise

ORD-Eintrag
ord-1eeee44df6504e6cbb7c79a72d33f360
Quelldatensatz
uspto-grants-2011_06
Patentnummer
US07968570B2

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