Ammonium Hydroxide → 2-Oxoindoline-5-sulfonamide
Reaktionsgleichung
Cl[S:2]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[CH2:8]2)(=[O:4])=[O:3].[OH-].[NH4+:16]>C(O)C>[NH2:16][S:2]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[CH2:8]2)(=[O:4])=[O:3]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
5-Chlorosulfonyl-2-oxindole (2.1 g) was added to 10 mL of ammonium hydroxide in 10 mL of ethanol and stirred at room temperature overnight. The mixture was concentrated and the solid collected by vacuum filtration to give 0.4 g (20% yield) of the title compound as an off-white solid.
Aufarbeitung
- concentrationThe mixture was concentrated
- filtrationthe solid collected by vacuum filtration
Quellen und Nachweise
- ORD-Eintrag
- ord-2520af5761ac4f8b8d7b07549287ce02
- Quelldatensatz
- uspto-grants-2005_02
- Patentnummer
- US06855730B2
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