Methyl 2-(2-nitro-4-(trifluoromethyl)phenyl)acetate → 6-Trifluoromethyloxindole

HRID 24314

Reaktionsgleichung

Reaktionsgleichung von HRID 24314
[N+:1]([C:4]1[CH:9]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:7]=[CH:6][C:5]=1[CH2:14][C:15]([O:17]C)=O)([O-])=O>[Pd]>[F:11][C:10]([F:13])([F:12])[C:8]1[CH:9]=[C:4]2[C:5]([CH2:14][C:15](=[O:17])[NH:1]2)=[CH:6][CH:7]=1

Komponenten

3

Edukt 1

HCID 83569Methyl 2-(2-nitro-4-(trifluoromethyl)phenyl)acetate

Produkt 1

HCID 6084876-Trifluoromethyloxindole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

Methyl 2-nitro-4-trifluoromethylphenylacetate (26 mg) was hydrogenated over 10% palladium on carbon and then heated at 100° C. for 3 hours. The catalyst was removed by filtration and the solvent evaporated to give the title compound.

Aufarbeitung

  1. customThe catalyst was removed by filtration
  2. customthe solvent evaporated

Quellen und Nachweise

ORD-Eintrag
ord-7cbd983c068145798984700036a97b65
Quelldatensatz
uspto-grants-2005_02
Patentnummer
US06855730B2

Verknüpfte Notizen

Wird geladen…