Triphenylphosphine → N-Boc-Imino-(triphenyl)phosphorane

HRID 244927Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 244927
[C:1]([N:8]=[N+]=[N-])(=[O:7])[O:2][C:3]([CH3:6])([CH3:5])[CH3:4].[C:11]1([P:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(OCC)C>[C:24]1([P:17]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[N:8][C:1]([O:2][C:3]([CH3:6])([CH3:5])[CH3:4])=[O:7])[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

Komponenten

4

Edukt 2

HCID 11776TriphenylphosphineHCID 61256Carbonazidic acid, 1,1-dimethylethyl ester

Produkt 1

HCID 2756802N-Boc-Imino-(triphenyl)phosphorane

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

To the solution of t-butyl carbonazidate in diethyl ether, 49.6 g (0.189 mol) of triphenylphosphine was added in small portions under cooling with ice, and the reaction solution was stirred at room temperature for 1 hour, and the precipitated solid was collected by filtration, washed with 200 mL of hexane and dried under reduced pressure to give 67 g of the desired product as white crystals.

Aufarbeitung

  1. temperatureunder cooling with ice
  2. filtrationthe precipitated solid was collected by filtration
  3. washwashed with 200 mL of hexane
  4. customdried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-05f3fdf7355f476b92d59ee2abcadbb6
Quelldatensatz
uspto-grants-2014_02
Patentnummer
US08658686B2

Notizen zur Reaktion

Wird geladen…