Benzene, (triethoxymethyl)- → 1-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

HRID 24725

Reaktionsgleichung

Reaktionsgleichung von HRID 24725
[C:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH2:6][C:5]1=[O:13])(=[O:3])[CH3:2].[CH3:14][CH2:15][O:16][C:17](OCC)(OCC)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C(OC(=O)C)(=O)C>[C:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:17]([O:16][CH2:15][CH3:14])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:13])(=[O:3])[CH3:2]

Komponenten

4

Edukt 2

HCID 74268Benzene, (triethoxymethyl)-HCID 3237191-Acetylindolin-2-one

Produkt 1

HCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7918Acetic AnhydrideLösungsmittel

Versuchsvorschrift

35.0 g (0.2 mol) of 1-acetyl-2-indolinone are dissolved in 300 ml of acetic anhydride and after the addition of 135 g (0.6 mol) of triethyl orthobenzoate the mixture is refluxed for 22 hours. The solvent is distilled off and the residue diluted with petroleum ether. After 18 hours' standing at ambient temperature, the crystalline precipitate is suction filtered, washed and dried.

Aufarbeitung

  1. temperatureis refluxed for 22 hours
  2. distillationThe solvent is distilled off
  3. additionthe residue diluted with petroleum ether
  4. filtrationfiltered
  5. washwashed
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-9cad90a0f5794d64b7d4ec75067742a0
Quelldatensatz
uspto-grants-2005_02
Patentnummer
US06855710B2

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