Tetrahydrothiophene → Phenacyltetrahydrothiophenium bromide

HRID 24964

Reaktionsgleichung

Reaktionsgleichung von HRID 24964
[S:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:6]([Br:15])[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8]>C(#N)C>[Br-:15].[CH2:6]([S+:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8]

Komponenten

4

Edukt 2

HCID 1127TetrahydrothiopheneHCID 6259Phenacyl bromide

Produkt 1

HCID 11346720Phenacyltetrahydrothiophenium bromideAusbeute 94,9 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel2×

Versuchsvorschrift

Tetrahydrothiophene (53.2 g) was dissolved in 400 ml of acetonitrile, and thereto was slowly added a solution obtained by dissolving 100 g of phenacyl bromide in 300 ml of acetonitrile, and the solution was stirred at room temperature for 3 hours, thereby a powder was precipitated. The reaction solution was poured into 1,500 ml of ethyl acetate, and the powder was filtered out and dried, thus 137 g of phenacyltetrahydrothiophenium bromide was obtained.

Aufarbeitung

  1. additionwas slowly added a solution
  2. customobtained
  3. customa powder was precipitated
  4. additionThe reaction solution was poured into 1,500 ml of ethyl acetate
  5. filtrationthe powder was filtered out
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-92317603e81c4877acde22e58de207d2
Quelldatensatz
uspto-grants-2005_02
Patentnummer
US06858370B2

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