Hydrochloric Acid → 5-Acetyl-2-methoxybenzoic acid

Beteiligte Stoffe

Reaktionsschritte

Methyl 2-methoxy-5-acetylbenzoate (Step A, 3 g, 14.4 mmol) was dissolved in acetic acid (80 ml) and then treated with c HCl (28 ml). The reaction mixture was refluxed for 4 hours, concentrated under reduced pressure and lyophilized to provide the title compound as cream color solid, which was used without further purification.

Herkunft & Nachweise