(4-Bromo-3-methylphenyl)methanol → 4-Bromo-3-methylbenzaldehyde

HRID 250859

Reaktionsgleichung

Reaktionsgleichung von HRID 250859
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][OH:9])=[CH:4][C:3]=1[CH3:10]>ClCCl.[O-2].[O-2].[Mn+4]>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[O:9])=[CH:4][C:3]=1[CH3:10]

Komponenten

4

Edukt 1

HCID 10987288(4-Bromo-3-methylphenyl)methanol

Produkt 1

HCID 109215214-Bromo-3-methylbenzaldehydeAusbeute 105,2 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418406HCID 178418406, VerbindungKatalysatorHCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

3.7 g (43 mmol, 10 eq) of manganese dioxide are added to a solution of 900 mg (4.3 mmol, 1 eq) of (4-bromo-3-methylphenyl)methanol in 8 mL of dichloromethane. The reaction mixture is stirred for 12 hours at room temperature. The solid is filtered off and the solvent is evaporated off. 900 mg of 4-bromo-3-methylbenzaldehyde are obtained in oil form and used in the following reaction without further purification.

Aufarbeitung

  1. filtrationThe solid is filtered off
  2. customthe solvent is evaporated off

Quellen und Nachweise

ORD-Eintrag
ord-e8546c71de014eecac7cc34dc7f089c6
Quelldatensatz
uspto-grants-2011_01
Patentnummer
US07863332B2

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