Dimethylformamide → 2-Amino-3-bromo-5-chlorobenzoic acid
Reaktionsgleichung
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].CN(C)C=O.[Br:17]N1C(=O)CCC1=O>O>[NH2:1][C:2]1[C:10]([Br:17])=[CH:9][C:8]([Cl:11])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a mixture of 1.7 g of 2-amino-5-chlorobenzoic acid and 100 ml of N,N-dimethylformamide was added 1.8 g of N-bromosuccinimide at room temperature, and the mixture was stirred at room temperature for 10 hours. Water was poured into the reaction mixture, and a deposited precipitate was collected by filtration to obtain 1.1 g of 2-amino-3-bromo-5-chlorobenzoic acid of the formula:
Aufarbeitung
- filtrationa deposited precipitate was collected by filtration
Quellen und Nachweise
- ORD-Eintrag
- ord-5cce3e9f19aa4324b2fff2a463991124
- Quelldatensatz
- uspto-grants-2011_01
- Patentnummer
- US07867949B2
Notizen zur Reaktion
Wird geladen…