Pyridinium chloride → HCID 135741999, Verbindung
Reaktionsgleichung
S1C2C(O)=CC=CC=2C=N1.[F:11][C:12]1[C:20]2[S:19][N:18]=[CH:17][C:16]=2[C:15]([O:21]C)=[CH:14][CH:13]=1.Cl.N1C=CC=CC=1>>[F:11][C:12]1[CH:13]=[CH:14][C:15]([OH:21])=[C:16]2[C:20]=1[S:19][N:18]=[CH:17]2Komponenten
4
Versuchsvorschrift
A method similar to that described for the synthesis of benzo[d]isothiazol-7-ol in WO 04/043904 was used from 7-fluoro-4-methoxybenzo[d]isothiazole (500 mg, 27.32 mmol) and pyridine hydrochloride (2.5 g, 21.74 mmol) to give the title compound as grey solid (420 mg, 65%).
Quellen und Nachweise
- ORD-Eintrag
- ord-07a346b76c3547d189fc48bbcb9d8ec3
- Quelldatensatz
- uspto-grants-2011_01
- Patentnummer
- US07868017B2
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