2-Aminothiazole → phenyl N-(1,3-thiazol-2-yl)carbamate

HRID 252722

Reaktionsgleichung

[NH2:1][C:2]1[S:3][CH:4]=[CH:5][N:6]=1.Cl[C:8]([O:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:9]>>[S:3]1[CH:4]=[CH:5][N:6]=[C:2]1[NH:1][C:8](=[O:9])[O:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Komponenten

Edukt 2

HCID 21552-Aminothiazole

HCID 15891Phenyl chloroformate

Produkt 1

HCID 651148phenyl N-(1,3-thiazol-2-yl)carbamate

Versuchsvorschrift

Using analogous procedures to those described in Example 49, the appropriate 2-amino-1,3-thiazole was reacted with phenyl chloroformate and the phenyl N-(1,3-thiazol-2-yl)carbamate so obtained was reacted with the appropriate alkylamine to give the compounds described in Table II.

Quellen und Nachweise

ORD-Eintrag: ord-e48e550cbcf34822bef06c9844b018ff
Quelldatensatz: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07868188B2

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