1,1,1,3,3,3-Hexafluoropropane → 1-Chloro-1,1,3,3,3-pentafluoropropane

A 600 mL, magnetically stirred, model autoclave fitted with a condenser (maintained at -10° C.), was evacuated, cooled to about -40° C., and charged with 0.6.9 g (0.036 mol) TiCl4 followed by 64 g (0.255 mol) CCl3CH2CCl3, and 102.5 g (5 mol) HF. The temperature was increased to 120° C. and maintained at that temperature for a total of 22 h. During the heating period, pressure in excess of 400 psig was periodically vented to an aqueous KOH scrubber which was attached to two -78° C. cold traps. At the end of the heating period, the remainder of the autoclave contents were slowly vented. The cold traps contained 36.1 g material which by GC analysis, contained 14.5% CF3CH2CF3 and 84.0% CF3CH2 CF2Cl, corresponding to a yield for CF3CH2CF2Cl of 69%.

1. custommodel autoclave fitted with a condenser
2. customwas evacuated
3. temperaturecooled to about -40° C.
4. temperatureThe temperature was increased to 120° C.
5. temperaturemaintained at that temperature for a total of 22 h
6. customwas attached to two -78° C.

ORD-Eintrag

ord-e7b93282e05f4addbe5f6faab80d2b9a

Quelldatensatz

uspto-grants-1998_03

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US05728904