2-Chlorocyclopentanone → 5,6-Dihydro-4H-cyclopenta[d]thiazol-2-amine hydrochloride

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A mixture of 2-chlorocyclopentanone (5.00 g, 39.5 mmol) and thiourea (3.00 g, 39.5 mmol) was heated at 80° C. for 3-4 minutes. After cooling to room temperature, the mixture was triturated with ethanol and the solid was collected by filtration to afford the title compound. MS (ESI) m/z 141 (M+H)+.

Herkunft & Nachweise