Chloroform → 2,3-Dichloro-4-acryloylphenol

HRID 255942Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 255942
[Cl:1][C:2]1[C:7]([Cl:8])=[C:6]([C:9](=[O:13])[CH2:10][CH2:11]Cl)[CH:5]=[CH:4][C:3]=1[OH:14].C([O-])(=O)C.[K+].C(Cl)(Cl)Cl>CO>[Cl:1][C:2]1[C:7]([Cl:8])=[C:6]([C:9](=[O:13])[CH:10]=[CH2:11])[CH:5]=[CH:4][C:3]=1[OH:14]

Komponenten

5

Edukt 3

HCID 6212ChloroformHCID 517044Potassium AcetateHCID 139587452,3-Dichloro-4-(3-chloropropionyl)phenol

Produkt 1

HCID 139587442,3-Dichloro-4-acryloylphenolAusbeute 83,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel2×

Versuchsvorschrift

A solution of 2,3-dichloro-4-(3-chloropropionyl)phenol (8.4 g, 0.033 mole) in methanol (30 ml) and potassium acetate (3.5 g, 0.033 mole) in methanol (30 ml) were united and refluxed for 20 minutes. The mixture was treated with chloroform (200 ml), washed with water, dried over MgSO4, filtered and the solvent removed from the filtrate by evaporation in vacuo. The residue was recrystallized from carbon tetrachloride to give 6 g of 2,3-dichloro-4-acryloylphenol, m.p. 135°-137° C.

Aufarbeitung

  1. temperaturerefluxed for 20 minutes
  2. washwashed with water
  3. dry with materialdried over MgSO4
  4. filtrationfiltered
  5. customthe solvent removed from the filtrate by evaporation in vacuo
  6. customThe residue was recrystallized from carbon tetrachloride

Quellen und Nachweise

ORD-Eintrag
ord-10094d4c6ace4cf3b1ec53d78396c7b1
Quelldatensatz
uspto-grants-1987_10
Patentnummer
US04699926

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