1-[2-(Benzyloxycarbonylamino)propanoyl]-2,2-dimethyl-4-imidazolidinone → 1-(2-Aminopropanoyl)-2,2-dimethyl-4-imidazolidinone

HRID 256356

Reaktionsgleichung

Reaktionsgleichung von HRID 256356
C(OC([NH:11][CH:12]([CH3:23])[C:13]([N:15]1[CH2:19][C:18](=[O:20])[NH:17][C:16]1([CH3:22])[CH3:21])=[O:14])=O)C1C=CC=CC=1.[H][H]>[Pd]>[NH2:11][CH:12]([CH3:23])[C:13]([N:15]1[CH2:19][C:18](=[O:20])[NH:17][C:16]1([CH3:22])[CH3:21])=[O:14]

Komponenten

4

Edukt 2

HCID 201637151-[2-(Benzyloxycarbonylamino)propanoyl]-2,2-dimethyl-4-imidazolidinoneHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 201637101-(2-Aminopropanoyl)-2,2-dimethyl-4-imidazolidinone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

An ethanolic solution of 1-[2-(benzyloxycarbonylamino)propanoyl]-2,2-dimethyl-4-imidazolidinone (4.9 g) containing 1 g of 5% palladium on charcoal was stirred at room temperature while hydrogen was bubbled into the solution for 1 hour. Removal of the catalyst, evaporation of the solvent, and trituration of the residue with ethyl acetate afforded the title compound as a white powder m.p. 156° C. (decomp).

Aufarbeitung

  1. customwas bubbled into the solution for 1 hour
  2. customRemoval of the catalyst, evaporation of the solvent, and trituration of the residue with ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-a0051da0bff6437eb70d71b84b48fe98
Quelldatensatz
uspto-grants-1987_10
Patentnummer
US04703054

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